Colon cancer deaths are on the rise while overall cancer deaths drop

13.7K
683
300
2025-11-10
Colon cancer deaths are on the rise while overall cancer deaths drop
Close up of a medical infusion device which delivers fluids, medications, blood and blood products to patients through IV.Share on Pinterest
Experts say cancer screening is crucial to preventing an increasing number of colon cancer deaths. Mo Lindsey Rivera/Stocksy
  • New data from the American Cancer Society shows that colorectal cancer deaths have continued to increase.
  • Meanwhile, overall cancer deaths have decreased in the United States.
  • Colon cancer is now the leading cause of cancer death in men under the age of 50 and second in women under 50 in the U.S.

The American Cancer Society recently released its Cancer Statistics 2024 report detailing the latest cancer facts and trends.


While the report shows that overall cancer deaths have continued to decline in the United States, some specific cancers — mainly colorectal cancer — have been seeing an increase in cancer deaths.


New data shows that colorectal cancer — also known as colon cancer — is now the leading cause of cancer death in men under the age of 50 and second in women under 50 in the U.S.


Why have colon cancer deaths increased? 

According to Rebecca Siegel, MPH, Senior Scientific Director of Surveillance Research at the American Cancer Society and lead author of this report, the success of tobacco control and a steep drop in deaths from lung cancer is a big part of why colorectal cancer deaths have increased in both men and women under the age of 50.


“But it is also because of increasing colorectal cancer incidence in people born after the 1950s for reasons that are currently under investigation by many researchers but may include increased obesity, changes in diet and/or the gut microbiome including highly processed food consumption, a more sedentary lifestyle, overuse of antibiotics, and even gut exposure to microplastics, etc.,” Siegal told Medical News Today.


“The rise in colorectal cancer in people under 50 is the same in men and women, strongly suggesting the cause is not hormonal or endogenous, but due to external environmental or behavioral changes,” she added.


Dr. Anton Bilchik, surgical oncologist, Chief of Medicine, and director of the Gastrointestinal and Hepatobiliary Program at Saint John’s Cancer Institute in Santa Monica, CA — who was not involved in this study — said another theory for this rise in colon cancer deaths might be inflammation.


“Inflammation has been shown to result in an increase in cardiovascular disease, as well as cancer,” Dr. Bilchik told MNT. “The concern is that a lot of this starts at a very young age and that education needs to start really at preschool in terms of what kids are eating and the importance of not living a sedentary lifestyle,” he added.


Dr. Steven Lee-Kong, professor of surgery and chief of the Division of Colorectal Surgery at Hackensack University Medical Center in New Jersey — who was also not involved in this study — said some potential factors that may be involved in the increase in colon cancer deaths might be, “poorer compliance to preventative health screening examinations, poorer health insurance coverage, lack of familiarity with family history — as this may contribute to increased risk of colorectal cancer — and lack of familiarity with the recent reduction in age at which patients are screened.”


What to know about colorectal or colon cancer

Colorectal cancer affects the colon — a part of the large intestine — and the rectum.


It is currently the third most common cancer in the world.


Colon cancer is normally seen in older adults over the age of 50. However, it can happen at any age, and previous studies show colorectal cancer diagnoses have almost doubled among young adults.


Typical symptoms of colon cancer include:


  • bloody stool
  • frequent diarrhea or constipation
  • stomach pain, cramps, and/or bloating
  • fatigue
  • unexplained weight loss

This type of cancer normally starts from cell clumps called polyps that grow inside the colon. While they are not automatically cancerous, they can become colon cancer over time.


Polyps can be found during regular screening tests, which are recommended for adults ages 45 to 75 and then removed.


The sooner colorectal cancer is spotted, the better the treatment options and potential outcome — the five-year survival rate is 91% if the cancer is found before it spreads outside of the colon or rectum.


Reducing risk of colorectal cancer key to preventing deaths

When asked how these increases in colon cancer deaths could be halted, Siegel said it’s challenging because the cause isn’t known.


“But there are many ways to reduce your risk of colorectal cancer in general by getting screened according to recommendations, maintaining a healthy body weight, being physically active, limiting consumption of red/processed meat and alcohol, and not smoking,” she continued.


“It’s also important to follow up with your doctor if you have persistent symptoms like blood in the stool or from the rectum, abdominal pain, change in bowel habits or shape of stool, etc.,” Siegel added.


Dr. Lee-Kong said he is increasingly alarmed by the continued, and poorly understood, increase in colorectal cancer incidence in younger adults.


“Compounded by the continued disparities seen in patients of color, colorectal cancer incidence and mortality needs to be better understood,” he added.


Can colon cancer screenings help decrease deaths? 

For colorectal cancer screenings, Siegel said certain action items should be followed.


“Increase screening before (age) 45 for people at higher risk by (age) 45 for everyone else,” she detailed. “Increase awareness of the increased risk and symptoms so people will go to the doctor and get diagnosed earlier, when treatment is more successful. And reduce the stigma so people will be more comfortable talking about the disease and their symptoms.”


Dr. Bilchik said the bottom line is that people need to recognize that cancers such as colon cancer and prostate cancer are preventable and that there are very good screening methods out there.


“We have very sensitive home stool-based tests that are more than 92% sensitive for detecting cancer cells,” he continued. “So it doesn’t have to be a colonoscopy alone. It’s much simpler in terms of being able to not have to do a bowel prep and be tested at home.


“Although colonoscopy is still the gold standard and certainly recommended in high-risk individuals, there are much easier, less expensive, and more convenient alternatives,” Dr. Bilchik added.


How can I protect myself from colon cancer? 

When it comes to protecting yourself from colon cancer, Dr. Lee-Kong advised to, “actively discuss family history with your primary care physician, don’t ignore changes in bowel habits or anal bleeding, (and) get screened starting at age 45.”


And Dr. Bilchik provided these basic tips for defending against colorectal cancer:


  • Exercise at least five days a week for 30 to 40 minutes at a time
  • Avoid processed food as much as possible
  • Limit the intake of red meat, as previous research shows that too much red meat is associated with colon cancer
  • Don’t ignore symptoms such as rectal bleeding, stomach pain, and weight loss
  • Avoid smoking
  • When you go to a grocery store, shop the outside, where fruits, vegetables, and healthier foods are located, rather than the inside, where a lot of processed foods can be found

Article "tagged" as:

Related Article

What to Know Before Taking Colostrum Supplements
18.6K
745
290

What to Know Before Taking Colostrum Supplements

Colostrum is a nutrient-dense, milky fluid that is first released from the breast when a mammal is b
Regular Sleep Schedule Linked to Lower Mortality Risk
28K
2.5K
1.1K

Regular Sleep Schedule Linked to Lower Mortality Risk

New research found that sleep regularity is more important than sleep duration.Another study found t
Alzheimer's risk: Researchers look for ways to lower neuroinflammation
43.9K
4K
750

Alzheimer's risk: Researchers look for ways to lower neuroinflammation

Share on PinterestResearchers are looking for more effective ways to deliver a potential therapy aga
Colon cancer deaths are on the rise while overall cancer deaths drop
13.7K
683
300

Colon cancer deaths are on the rise while overall cancer deaths drop

Share on PinterestExperts say cancer screening is crucial to preventing an increasing number of colo
Experts Share Their Top Food Safety Rules
35.9K
3.6K
359

Experts Share Their Top Food Safety Rules

The federal government estimates that there are approximately 48 million cases of foodborne illness
Ozempic weight loss plateau: What is it and how to get past it
12.5K
876
157

Ozempic weight loss plateau: What is it and how to get past it

Share on PinterestAfter using Ozempic for a while, many people may reach a plateau with their weight
Lifting Weights Might Help Prevent Skin Aging, Study Shows
36.2K
1.4K
202

Lifting Weights Might Help Prevent Skin Aging, Study Shows

New research shows resistance training—also called strength training or sometimes weight lifting—may
Can semen microbiome health affect male infertility?
3.4K
169
65

Can semen microbiome health affect male infertility?

Share on PinterestBacterial imbalances in the semen microbiome may cause a reduction in semen and sp
IVF: Mediterranean diet, some supplements may increase success rate
24.4K
730
313

IVF: Mediterranean diet, some supplements may increase success rate

Share on PinterestEating a Mediterranean diet may help with IVF success, new research suggests. Nadi
Becky G stuns in show-stopping looks at Paris’s fashion event
40.5K
809
145

Becky G stuns in show-stopping looks at Paris’s fashion event

Becky G, the multi-talented singer, actress, and entrepreneur, recently graced the fashion capital o
Elevating the Game: NHL's Stylish Collaboration with Lululemon and Fanatics
48.1K
1.9K
192

Elevating the Game: NHL's Stylish Collaboration with Lululemon and Fanatics

The National Hockey League has announced a new partnership with Lululemon and Fanatics to launch a p
PICS: Muireann O’Connell steps out in style to host Day One of Blanchardstown Centre‘s Fashion & Beauty Festival with Goss.ie
25K
2K
678

PICS: Muireann O’Connell steps out in style to host Day One of Blanchardstown Centre‘s Fashion & Beauty Festival with Goss.ie

Muireann O'Connell hosted the first day of the Blanchardstown Centre's Fashion & Beauty Festival, sh
Bianca Jagger: A Legacy of Style, Freedom, and Empowerment
32.4K
2.3K
589

Bianca Jagger: A Legacy of Style, Freedom, and Empowerment

Bianca Jagger, a longtime advocate of menswear-inspired fashion, has consistently embraced suits as
Moncler Genius to Close out Shanghai Fashion Week SS25
27.5K
1.7K
297

Moncler Genius to Close out Shanghai Fashion Week SS25

Moncler is set to showcase its Moncler Genius event at Shanghai Fashion Week on October 19, building
Fashion Industry Unites to Aid Los Angeles Wildfire Victims
16.5K
824
329

Fashion Industry Unites to Aid Los Angeles Wildfire Victims

Fashion and beauty brands are uniting to support victims of the devastating wildfires in Los Angeles
Jamaican-American Hope Wade: World class fashion design
22.8K
1.8K
383

Jamaican-American Hope Wade: World class fashion design

The East Ramapo Central School District celebrated Women's History Month by honoring local women who
Designer Simone Rocha Demands 'Free Palestine' at Fashion Awards
38.8K
1.6K
697

Designer Simone Rocha Demands 'Free Palestine' at Fashion Awards

Simone Rocha received the British Womenswear Designer Award at The Fashion Awards 2024 in London. Th
Five destinations for Indians who love fashion
38.6K
386
162

Five destinations for Indians who love fashion

The article explores the world of budget shopping, highlighting popular shopping destinations across
Top Hair Trends to Transform Your Look in 2025
30.3K
2.1K
550

Top Hair Trends to Transform Your Look in 2025

Looking ahead to 2025, several hair trends are set to dominate. Shorter styles like the "French Girl
How Diane von Furstenberg’s Wrap Dress Made Fashion History
40.2K
2.4K
627

How Diane von Furstenberg’s Wrap Dress Made Fashion History

The article discusses the impact of Diane von Furstenberg's iconic wrap dress, which has become a sy